First Appearance: Marvel Spotlight (vol.1) #32
Poisoned by the plentiful uranium on the property of her father, a young Jessica Drew was given an experimental serum derived from the blood of several species of spider and then placed in a genetic accelerator until she could heal. Unfortunately, Jessica was caught in the accelerator for decades, and awoke in a strange new world with no memory of her past and a host of strange new powers. Eventually finding herself in Hydra's orbit, the terrorist group tried to train her to be a perfect assassin only to have her rebel against them. Since then she has had a series of interesting adventures as Spider-Woman.